Pacient\u00ebt me nj\u00eb form\u00eb t\u00eb kancerit t\u00eb gjakut q\u00eb m\u00eb par\u00eb nuk trajtohej, tani jetojn\u00eb pa s\u00ebmundje pas nj\u00eb terapie gjenetike, e para n\u00eb bot\u00eb. Alyssa Tapley, 16 vje\u00e7, u b\u00eb pacientja e par\u00eb me nj\u00eb form\u00eb agresive t\u00eb leu\u00e7emis\u00eb q\u00eb iu n\u00ebnshtrua trajtimit eksperimental n\u00eb vitin 2022. Ajo po shqyrtonte mund\u00ebsit\u00eb p\u00ebr kujdes paliativ, por tani \u00ebsht\u00eb sh\u00ebndosh\u00eb e mir\u00eb. Tani jan\u00eb publikuar rezultate t\u00eb reja t\u00eb nj\u00eb prove klinike me tet\u00eb f\u00ebmij\u00eb dhe dy t\u00eb rritur t\u00eb tjer\u00eb n\u00eb Spitalin Great Ormond Street (GOSH) dhe Spitalin King’s College n\u00eb Lond\u00ebr. Dy t\u00eb tretat kan\u00eb qen\u00eb pa s\u00ebmundje deri n\u00eb tre vjet.<\/p>\n
Dr. Deborah Yallop, hematologe konsulente tha: “Kemi par\u00eb p\u00ebrgjigje mbres\u00ebl\u00ebn\u00ebse n\u00eb trajtimin e leu\u00e7emis\u00eb q\u00eb dukej e pash\u00ebrueshme – \u00ebsht\u00eb nj\u00eb qasje shum\u00eb e fuqishme.” Pacient\u00ebt n\u00eb studim kishin leu\u00e7emi limfoblastike akute t\u00eb qelizave T, nj\u00eb form\u00eb e rrall\u00eb e kancerit t\u00eb gjakut q\u00eb vjen si pasoj\u00eb e rritjes s\u00eb pakontrollueshme t\u00eb qelizave T n\u00eb sistemin imunitar. T\u00eb gjith\u00eb nuk kishin arritur t’i p\u00ebrgjigjeshin trajtimit ekzistues. K\u00ebshtu q\u00eb ekipi mjek\u00ebsor provoi nj\u00eb teknik\u00eb eksperimentale p\u00ebr t\u00eb shnd\u00ebrruar qelizat T t\u00eb marra nga nj\u00eb dhurues n\u00eb makina luftuese q\u00eb mundin kancerin.<\/p>\n
Teknika, e quajtur BE-CAR7, \u00ebsht\u00eb nj\u00eb mjet shum\u00eb i sakt\u00eb p\u00ebr ndryshimin e shkronjave individuale n\u00eb kodin gjenetik, manualin e udh\u00ebzimeve p\u00ebr t\u00eb gjitha qelizat n\u00eb trup. Ndryshimi i vet\u00ebm nj\u00eb shkronje – ajo q\u00eb shkenc\u00ebtar\u00ebt e quajn\u00eb “baza” t\u00eb ADN-s\u00eb – mund t\u00eb ndryshoj\u00eb funksionin e nj\u00eb gjeni n\u00eb t\u00eb nj\u00ebjt\u00ebn m\u00ebnyr\u00eb si\u00e7 z\u00ebvend\u00ebsimi i nj\u00eb shkronje t\u00eb vetme ky\u00e7e n\u00eb nj\u00eb mesazh tekst mund t\u00eb ndryshoj\u00eb kuptimin e tij. Shkenc\u00ebtar\u00ebt b\u00ebn\u00eb tre “redaktime baz\u00eb” individuale n\u00eb qelizat T t\u00eb donator\u00ebve, shkruan Sky News.<\/p>\n
Ndryshimet n\u00eb ADN i b\u00ebn\u00eb qelizat nj\u00eb trajtim “t\u00eb gatsh\u00ebm p\u00ebr t\u2019u p\u00ebrdorur” q\u00eb nuk kishte nevoj\u00eb t\u00eb p\u00ebrputhej me pacient\u00ebt si transplantet e tjera. Dhe ata gjithashtu i udh\u00ebzuan qelizat T t\u00eb dhuruesit t\u00eb shkat\u00ebrronin secil\u00ebn prej qelizave T t\u00eb pacientit – pavar\u00ebsisht n\u00ebse ishin kancerogjene apo jo. N\u00ebse t\u00eb gjitha qelizat T do t\u00eb zhdukeshin brenda kat\u00ebr jav\u00ebsh trajtimi, pacient\u00ebt do t\u00eb ishin n\u00eb gjendje t\u00eb vazhdonin dhe t\u2019i n\u00ebnshtroheshin nj\u00eb transplanti t\u00eb palc\u00ebs s\u00eb kockave p\u00ebr t\u00eb rind\u00ebrtuar nj\u00eb sistem imunitar t\u00eb sh\u00ebndetsh\u00ebm.<\/p>\n
<\/p>\n","protected":false},"excerpt":{"rendered":"
Pacient\u00ebt me nj\u00eb form\u00eb t\u00eb kancerit t\u00eb gjakut q\u00eb m\u00eb par\u00eb nuk trajtohej, tani jetojn\u00eb pa s\u00ebmundje pas nj\u00eb terapie gjenetike, e para n\u00eb bot\u00eb. Alyssa Tapley, 16 vje\u00e7, u b\u00eb pacientja e par\u00eb me nj\u00eb form\u00eb agresive t\u00eb leu\u00e7emis\u00eb q\u00eb iu n\u00ebnshtrua trajtimit eksperimental n\u00eb vitin 2022. Ajo po shqyrtonte mund\u00ebsit\u00eb p\u00ebr kujdes paliativ,<\/p>\n","protected":false},"author":1,"featured_media":13508,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2],"tags":[],"class_list":{"0":"post-13507","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-lifestyle"},"_links":{"self":[{"href":"https:\/\/revistatrend.com\/index.php\/wp-json\/wp\/v2\/posts\/13507","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/revistatrend.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/revistatrend.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/revistatrend.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/revistatrend.com\/index.php\/wp-json\/wp\/v2\/comments?post=13507"}],"version-history":[{"count":1,"href":"https:\/\/revistatrend.com\/index.php\/wp-json\/wp\/v2\/posts\/13507\/revisions"}],"predecessor-version":[{"id":13509,"href":"https:\/\/revistatrend.com\/index.php\/wp-json\/wp\/v2\/posts\/13507\/revisions\/13509"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/revistatrend.com\/index.php\/wp-json\/wp\/v2\/media\/13508"}],"wp:attachment":[{"href":"https:\/\/revistatrend.com\/index.php\/wp-json\/wp\/v2\/media?parent=13507"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/revistatrend.com\/index.php\/wp-json\/wp\/v2\/categories?post=13507"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/revistatrend.com\/index.php\/wp-json\/wp\/v2\/tags?post=13507"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}